Skip to main content
Patient Guide

Mounjaro (Tirzepatide) Quick Start

Everything you need to know about starting your tirzepatide program. Follow your physician's specific instructions.

Dosing Schedule

2.5 mg
Weeks 1–4 (start)
5 mg
Weeks 5+ (minimum 4 weeks)

Additional doses available: 7.5 mg, 10 mg, 12.5 mg, 15 mg. Your physician will determine the right dose for you. Mounjaro is taken once weekly, on the same day.

Changing your dose day

You may change the day as long as at least 3 days (72 hours) have passed since your last dose.

Missed a dose?

Take within 4 days (96 hours). If more than 4 days have passed, skip and resume your regular schedule. Do not take 2 doses within 3 days of each other.

How to Inject

1

Choose your injection site

Stomach or thigh (self-injection). Back of the upper arm (someone else injects). Your physician can help you decide.

2

Pull off the gray base cap

Make sure the pen is Locked. Pull the gray base cap off and discard. Do not put it back on or touch the needle.

3

Place on skin, then Unlock

Place the clear base flat against your skin at the injection site. Unlock by turning the lock ring.

4

Press and hold up to 10 seconds

Press and hold the purple injection button. Listen for 2 clicks: 1st click = injection started, 2nd click = injection completed. The gray plunger will be visible when done.

5

After your injection

Place the used pen in a sharps container immediately.

Storage

Standard storage

Store in original carton. Refrigerate at 36°F–46°F. Do not freeze.

Traveling

Can be kept out of refrigerator for up to 21 days. Keep below 86°F (30°C).

The pen contains glass parts. If dropped on a hard surface, do not use it — use a new pen instead.

Common Side Effects

NauseaDiarrheaDecreased appetiteVomitingConstipationIndigestionStomach pain

Most nausea and GI events occur while the dose is being increased and typically decrease over time.

Tips for managing nausea:

  • Eat smaller meals
  • Avoid fat or fatty foods
  • Try bland foods like toast, crackers, or rice
  • Stop eating when you feel full

Questions about your Mounjaro program?

(281) 666-9211